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This is a very interesting read, I've actually managed to understand the most of it. Mario May 7, at 4: At the same time that citrate synthase is inhibited there exists another enzyme in liver mitochondria that is activated named beta-ketothiolase. Chris March 17, at 9: Would TKD throw me out of ketosis? G March 12, at 4: The case for SFAs:


According to some studies in rats, it can inhibit a fat producing enzyme called Citrate Lyase, making it more difficult for the body to produce fat out of carbohydrates (1). Other rat studies show increased levels of the neurotransmitter serotonin.

This could theoretically lead to reduced appetite and cravings (2). There are actually a whole bunch of studies in rats showing that Garcinia Cambogia consistently leads to significant weight loss (3, 4, 5, 6).